Gervaise Henry

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Building data & AI platforms for genomics and multi-omics research. VP Solutions Engineering at Manifold — bench and computational biologist turned platform leader.

I’ve spent my career at the intersection of biology, data, and infrastructure: starting at the bench running high-throughput screens and single-cell RNA-seq, then moving into computational biology, cloud architecture, and ultimately leading the engineering organizations that build platforms for genomics and multi-omics research at scale. I’ve built and managed global teams of solutions architects, bioinformatics engineers, and services engineers across the US, Europe, and Asia. AWS Certified Solutions Architect & Cloud Practitioner. Certified Scrum Product Owner.

CSPO

Skills

Top Skills
  • Solutions Engineering Leadership
  • Genomics & Multi-Omics Platforms
  • Cloud Architecture (AWS)
Certifications
  • AWS Certified Solutions Architect - Associate
  • AWS Certified Cloud Practitioner
  • Scrum Alliance Certified Scrum Product Owner
Languages, Operating Systems & Tools
  • R
  • Python
  • Nextflow
  • WDL
  • git
  • linux
  • bash
Website Development
  • Static Site Generators
  • Serverless Deployment
  • GitLab Pages
  • html5
  • css3
  • javascript
Cloud Platforms
  • amazonwebservices
  • Azure
  • googlecloud
AWS Tools
  • S3
  • EC2
  • Batch
  • Lambda
  • DynamoDB
  • API Gateway
  • Certificate Manager
  • Route53
  • CloudFront
  • CloudTrail
  • Athena
Container Environments
  • Docker
  • Singularity
Biological Modalities
  • Bulk RNA-seq
  • Gene Expression Microarray
  • scRNA-seq
  • scTCR-seq
  • Spatial Transcriptomics
  • Variant Calling
  • Proteomics (Mass Spec)
  • Molecular Biology Techniques

Experience

VP Solutions Engineering

Manifold

Lead Solutions Engineering at Manifold, the AI platform for life sciences. Responsible for the technical customer-facing function spanning pre-sales and post-sales, partnering with sales, product, and engineering to win, deliver, and expand strategic customer relationships.

  • Building and scaling the Solutions Engineering organization, with direct reports spanning solutions leadership and forward deployed engineering, and expanding the team with additional Forward Deployed Builders to meet growing customer demand.
  • Provide technical leadership for Forward Deployed Engineers across the broader organization, guiding how they engage with customers on complex implementations even where reporting lines sit elsewhere.
  • Partner with the pre-sales Solutions team across the technical customer journey — contributing to discovery, scoping, proof-of-concept development, and platform demonstrations — while owning post-sales implementation, technical delivery, and ongoing customer partnership.
  • Maintain broad coverage across Manifold’s customer base with concentrated focus on strategic accounts — particularly high-risk, high-reward engagements where customer problems are technically complex and platform fit requires deep scientific and architectural collaboration.
  • Build proof-of-concept, reference implementation, and demo assets across three purposes: supporting pre-sales in customer acquisition, driving expansion within existing accounts, and extending platform functionality for broader customer applicability.
  • Partner with Product and Engineering to translate field signal into roadmap priorities and to stress-test new capabilities against customer needs before they ship.
  • Serve as a liaison between customers, sales, product, engineering, and support, ensuring customer technical and scientific needs are represented throughout the organization.

January 2026 - Present

VP, Head of Data Engineering

Champions Oncology, Inc.

Led data infrastructure and management strategy for Champions’ research and development efforts, with responsibility for the data platform supporting multi-omics and research data workflows in alignment with FAIR principles.

  • Set direction on modernizing Champions’ analytic pipelines, initiating rebuilds to bring them in line with current standards for reproducibility, maintainability, and scalability.
  • Migrated the analytic compute environment onto a foundation that delivered meaningful reductions in pipeline runtime and cost, improving the economics of recurring analyses.
  • Initiated the build-out of data provenance, lineage, and observability infrastructure — evaluating tooling and beginning implementation of the governance layer needed to support regulated multi-omics and research data at scale.
  • Owned data organization and deployment for new data commercialization efforts, structuring datasets for external availability and partnering with business stakeholders to bring data products to market.
  • Supported sales efforts as the senior scientific and technical voice, providing subject-matter expertise in customer conversations and shaping the technical positioning of data offerings.
  • Contributed to new assay development efforts, particularly on the analytical and data-handling side — advising on how downstream analysis requirements should shape assay design, data capture, and output structure.
  • Served as the senior technical voice for data strategy, partnering with R&D and executive leadership on platform direction, tooling selection, and long-term data architecture decisions.

January 2025 - January 2026

Head of Professional Services Engineering

DNAnexus

Led the Professional Services Engineering organization — a global team of 15–20 architects, bioinformatics engineers, services engineers, and contractors across the US, Europe, and Asia — responsible for all technical services delivery on the DNAnexus platform.

  • Expanded scope from leading the Solutions Engineering function to leading all technical staff across Professional Services, following consistent delivery improvements under prior management.
  • Oversaw services delivery across a global, distributed team — including customer-facing engineering, platform integrations, custom solution development, and data engineering for customer data ingestion.
  • Managed a sizeable offshore contractor contingent alongside full-time staff, balancing delivery throughput with margin discipline as the services function reached its highest profitability during this period amid continued scaling.
  • Partnered with Product Engineering and Product Management on roadmap priorities informed by customer delivery experience, and built proof-of-concept assets to support architectural decisions on new platform capabilities.
  • Served as a technical liaison between sales, customers, and internal product and support teams — deployed frequently to strategic or at-risk customer engagements to resolve escalations and restore delivery trajectory.

June 2024 - January 2025

Manager, Solutions Science Engineering

DNAnexus

Managed the Solutions Engineering organization through a period of leadership transition, expanding scope mid-tenure to include a subset of the Professional Services engineering team.

  • Led a team of 5–6 Solutions Engineers distributed across the US and EMEA, supporting presales engagements globally across all customer verticals.
  • Took on additional management responsibility for part of the Professional Services engineering function following a leadership vacuum, tightening integration between presales and services — notably in SOW scoping accuracy and services utilization — which led to subsequent promotion to Head of PS Engineering.
  • Built DNAnexus’s external technical presence in Europe and North America, delivering invited oral presentations at EU Biobank Week 2024, ACMG 2024, BioTechX Europe 2023, and the Precision Medicine Leaders Summit 2023, with additional panel participation at BioIT World 2023 on precision medicine and FAIR multimodal data.
  • Built and refined proof-of-concept and demo assets to demonstrate platform capabilities against customer-specific scientific and technical needs.
  • Partnered with Product Engineering and Product Management on roadmap prioritization based on field signal, and served as liaison between sales, customers, product, professional services, and support.

February 2023 - May 2024

Senior Solutions Engineer

DNAnexus

Individual contributor presales engineer supporting customers globally across all verticals, with particular depth in top-5 pharma and diagnostics.

  • Partnered with sales on customer discovery, scoping, and technical qualification — translating customer scientific and operational needs into platform-fit assessments and architectural proposals.
  • Built proof-of-concept assets to validate the DNAnexus platform against real customer workflows, including substantial WDL and Nextflow pipeline development and lift-and-shift work.
  • Delivered platform demonstrations, technical training, and white-glove technical support for strategic accounts throughout the presales cycle.
  • Served as technical liaison between sales, customers, and internal product, professional services, and support teams — recognized for technical depth and customer trust that led to first-line management responsibility following departures of other team leaders.

August 2021 - February 2023

Computational Biologist

UT Southwestern Medical Center

Applied computational, cellular, and molecular techniques to investigate normal biology of the lower urinary tract and the development and progression of benign and malignant pathologies. Focused on single-cell and bulk RNA-sequencing of FACS-sorted populations to characterize normal and diseased cellular heterogeneity. Developed and deployed standardized pipelines for data analysis and exploration, including cloud-based (AWS, Azure) implementations.

September 2019 - July 2021

Research Associate

UT Southwestern Medical Center

Designed, conducted, and analyzed cellular and molecular experiments investigating normal prostate biology and the development and progression of benign prostatic hyperplasia and prostate cancer. Leveraged single-cell and bulk RNA-sequencing of FACS-sorted populations to characterize cellular heterogeneity in healthy and diseased tissue, and identified immune infiltrate signatures in primary human prostate samples to associate with cell-type-specific gene expression, epithelial dynamics, and clinical outcomes. First or co-authored eight journal publications during this period, including a first-author paper in Cell Reports (2018).

April 2015 - September 2019

Research Associate

Harbor Branch Oceanographic Institute at Florida Atlantic University

Developed high-content image-based assays for high throughput drug discovery. Optimized high throughput assays for early-stage drug discovery on marine natural products.

November 2014 - March 2015

RA/TA

American University

Used cellular and molecular biology techniques to investigate the effect of adipocytes and obesity on the multiple myeloma bone marrow tumor microenvironment. Techniques included cell culture (including co-culture), immunoblotting, ELISA, qPCR, tubulogenesis assays, invasion assays, viability assays, immunofluorescence, and confocal microscopy. Independently taught undergraduate lab courses, including design of laboratory content, assessments, grading, and student counseling.

Courses taught: Bio 200 Structure and Function of the Human Body, Bio 210 General Biology II, Bio 300 Cell Biology, Bio 356 Genetics.

August 2012 - May 2014

Lab Technician

UT Southwestern Medical Center

Investigated the relationship between the peptidyl-prolyl cis/trans isomerase Pin1 and IL13 in asthma models, using cellular, molecular, and biochemical techniques. Managed lab budget, ordering, and vendor relationships.

September 2011 - May 2012

Screening Scientist

UT Southwestern Medical Center

Conducted high-throughput compound and RNAi screens in the HTS/RNAi Core, working with a 200,000-compound library, whole-genome human siRNA, Drosophila dsRNA, and custom libraries. Primary project used compound and RNAi screens to functionally categorize NSCLC cell lines into familial groups, identifying molecular susceptibilities exploitable based on biomarkers. Contributed across all aspects of projects: assay choice and development, optimization, implementation, data analysis, bioinformatics, and follow-up experiments. Additional projects included screens for osteoclast differentiation modifiers, novel-mechanism antimicrobial agents, iron homeostasis regulators (siRNA), and miRNA sensitizers to sub-lethal chemotherapy in cancer cells with specific genetic profiles.

February 2010 - September 2011

Summer Undergraduate Research Intern

Harbor Branch Oceanographic Institution

Screened for NF-κB inhibitors using a cell-based luciferase reporter assay on a library of partially purified marine natural products. Confirmed prospective inhibitors via flow cytometry and immunoblotting, and identified active compounds using HPLC, MS, and 1D/2D NMR.

May - August 2008

The Journal of Pathology - 5-alpha reductase inhibitors induce a prostate luminal to club cell transition in human benign prostatic hyperplasia

Joseph DB, Henry GH, Malewska A, Reese JC, Mauck RJ, Gahan JC, Hutchinson RC, Mohler JL, Roehrborn CG, Strand DW
Benign prostatic hyperplasia (BPH) is a non-malignant expansion of peri-urethral prostate tissue that affects half of aging men. 5-alpha reductase inhibitors (5ARIs) are used as a frontline therapy for BPH to shrink prostate volume by blocking the conversion of testosterone to dihydrotestosterone (DHT). Low DHT levels elicit luminal epithelial apoptosis, but the histologic response to 5ARI treatment is often heterogeneous and lower urinary tract symptoms often persist, requiring surgical intervention. We used two spatial transcriptomics profiling approaches to characterize gene expression changes across histologically normal and atrophied regions in prostates from 5ARI-treated men. Using the Visium spatial gene expression platform, we showed that atrophied acini from 5ARI-treated patients with decreased epithelial infolding and reduced lumen size had increased club cell gene expression. The spectrum of morphological atrophy changes in prostate acini from 5ARI-treated patients correlated with reduced androgen receptor signaling and increased expression of urethral club cell genes including LTF, PIGR, OLFM4, SCGB1A1, and SCGB3A1. Prostate luminal cells within atrophied acini also adapted to low DHT conditions by increasing NF-κB signaling and anti-apoptotic BCL2 expression, which may explain their survival. Using nanoString GeoMx digital spatial profiling, we confirmed that histologically atrophied acini expressing SCGB3A1 displayed higher levels of club cell markers compared to histologically normal, NKX3-1+ regions that retained prostate identity. In addition, club-like cells within regions of 5ARI-induced prostate atrophy closely resembled club cells from the urethral epithelium. A comparison of histologically normal regions from untreated men and histologically normal regions from 5ARI-treated men revealed only few transcriptional differences, highlighting the mixed response to 5ARI treatment where some acini are unaffected. Together, our results describe a heterogeneous response to 5ARI treatment where some epithelial regions undergo an epithelial adaptation from a prostate secretory luminal cell to a club cell-like state.
December 2021

The Journal of Pathology - Single cell analysis of mouse and human prostate reveals novel fibroblasts with specialized distribution and microenvironment interactions

Joseph DB, Henry GH, Malewska A, Reese JC, Mauck RJ, Gahan JC, Hutchinson RC, Malladi VS, Roehrborn CG, Vezina CM, Strand DW
Stromal-epithelial interactions are critical to the morphogenesis, differentiation and homeostasis of the prostate, but the molecular identity and anatomy of discrete stromal cell types is poorly understood. Using single cell RNA-sequencing, we identified and validated the in situ localization of three smooth muscle subtypes (prostate smooth muscle, pericytes and vascular smooth muscle) and two novel fibroblast subtypes in human prostate. Peri-epithelial fibroblasts (APOD+) wrap around epithelial structures while interstitial fibroblasts (C7+) are interspersed in extracellular matrix. In contrast, the mouse displayed three fibroblast subtypes with distinct proximal-distal and lobe specific distribution patterns. Statistical analysis of mouse and human fibroblasts showed transcriptional correlation between mouse prostate (C3+) and urethral (Lgr5+) fibroblasts and the human interstitial fibroblast subtype. Both urethral fibroblasts (Lgr5+) and ductal fibroblasts (Wnt2+) in the mouse contribute to a proximal Wnt/Tgfb signaling niche that is absent in human prostate. Instead, human peri-epithelial fibroblasts express secreted WNT inhibitors SFRPs and DKK1, which could serve as a buffer against stromal WNT ligands by creating a localized signaling niche around individual prostate glands. We also identified proximal-distal fibroblast density differences in human prostate that could amplify stromal signaling around proximal prostate ducts. In human Benign Prostatic Hyperplasia, fibroblast subtypes upregulate critical immunoregulatory pathways and show distinct distributions in stromal and glandular phenotypes. A detailed taxonomy of leukocytes in BPH reveals an influx of myeloid dendritic cells, T cells and B cells, resembling a mucosal inflammatory disorder. A receptor-ligand interaction analysis of all cell types revealed a central role for fibroblasts in growth factor, morphogen and chemokine signaling to endothelia, epithelia and leukocytes. These data are foundational to the development of new therapeutic targets in benign prostatic hyperplasia.
June 2021

The Prostate - Urethral luminal epithelia are castration-insensitive cells of the proximal prostate

Joseph DB, Henry GH, Malewska A, Iqbal NS, Ruetten HM, Turco AE, Abler LL, Sandhu SK, Cadena MK, Malladi VS, Reese JC, Mauck RJ, Gahan JC, Hutchinson RC, Roehrborn CG, Baker LA, Vezina CM, Strand DW
Castration‐insensitive epithelial progenitors capable of regenerating the prostate have been proposed to be concentrated in the proximal region based on facultative assays. Functional characterization of prostate epithelial populations isolated with individual cell surface markers has failed to provide a consensus on the anatomical and transcriptional identity of proximal prostate progenitors. Here, we use single‐cell RNA sequencing to obtain a complete transcriptomic profile of all epithelial cells in the mouse prostate and urethra to objectively identify cellular subtypes. Pan‐transcriptomic comparison to human prostate cell types identified a mouse equivalent of human urethral luminal cells, which highly expressed putative prostate progenitor markers. Validation of the urethral luminal cell cluster was performed using immunostaining and flow cytometry. Our data reveal that previously identified facultative progenitors marked by Trop2, Sca-1, KRT4, and PSCA are actually luminal epithelial cells of the urethra that extend into the proximal region of the prostate, and are resistant to castration‐induced androgen deprivation. Mouse urethral luminal cells were identified to be the equivalent of previously identified human club and hillock cells that similarly extend into proximal prostate ducts. Benign prostatic hyperplasia (BPH) has long been considered an “embryonic reawakening,” but the cellular origin of the hyperplastic growth concentrated in the periurethral region is unclear. We demonstrate an increase in urethral luminal cells within glandular nodules from BPH patients. Urethral luminal cells are further increased in patients treated with a 5‐α reductase inhibitor. Our data demonstrate that cells of the proximal prostate that express putative progenitor markers, and are enriched by castration in the proximal prostate, are urethral luminal cells and that these cells may play an important role in the etiology of human BPH.
June 2020

Cell Reports - A cellular anatomy of the normal human prostate

Henry GH, Malewska A, Joseph DB, Malladi VS, Lee J, Torrealba J, Mauck RJ, Gahan JC, Raj GV, Roehrborn CG, Hon GC, MacConmara MP, Reese JC, Hutchinson RC, Vezina CM, Strand DW
A comprehensive cellular anatomy of normal human prostate is essential for solving the cellular origins of benign prostatic hyperplasia and prostate cancer. The tools used to analyze the contribution of individual cell types are not robust. We provide a cellular atlas of the young adult human prostate and prostatic urethra using an iterative process of single-cell RNA sequencing (scRNA-seq) and flow cytometry on ∼98,000 cells taken from different anatomical regions. Immunohistochemistry with newly derived cell type-specific markers revealed the distribution of each epithelial and stromal cell type on whole mounts, revising our understanding of zonal anatomy. Based on discovered cell surface markers, flow cytometry antibody panels were designed to improve the purification of each cell type, with each gate confirmed by scRNA-seq. The molecular classification, anatomical distribution, and purification tools for each cell type in the human prostate create a powerful resource for experimental design in human prostate disease.
December 2018

Cytometry Part A - OMIP-040: Optimized gating of human prostate cellular subpopulations

Henry GH, Loof N, Strand DW
This panel was optimized to quantify the relative frequency of the major cell types present in the human prostate in addition to their sorting for downstream applications. Tissue resident white blood cells (referred to here as leukocytes) are identified by CD45, epithelia are identified by CD326, and stroma are double negative with those markers. Epithelia can be further segregated into basal, luminal, and “other” populations using CD26 and CD271. Fibromuscular stroma can be identified by removing CD31‐positive endothelia from the stroma. This panel can also serve as a backbone for the addition of markers to interrogate subpopulations within these major cell types. The panel has been validated on freshly digested and cryopreserved human prostate cells collected from young organ donors, BPH patients, and prostate cancer patients. Other tissue types have not been tested. Other basal cell markers including CD49f, podoplanin, and CD104 are tested and compared with CD271.
August 2017

The Prostate - Molecular pathogenesis of human prostate basal cell hyperplasia

Henry GH, Malewska A, Hutchinson R, Gahan J, Mauck R, Francis F, Torrealba J, Roehrborn C, Strand DW
Background: Understanding the molecular pathogenesis of distinct phenotypes in human benign prostatic hyperplasia (BPH) is essential to improving therapeutic intervention. Current therapies target smooth muscle and luminal epithelia for relief of lower urinary tract symptoms (LUTS) due to BPH, but basal cell hyperplasia (BCH) remains untargeted. The incidence of BCH has been reported at 8‐10%, but a molecular and cellular characterization has not been performed on this phenotype. Methods: Using freshly digested tissue from surgical specimens, we performed RNA‐seq analysis of flow cytometry‐purified basal epithelia from 3 patients with and 4 patients without a majority BCH phenotype. qPCR was performed on 28 genes identified as significant from 13 non‐BCH and 7 BCH specimens to confirm transcriptomic analysis. IHC was performed on several non‐BCH and BCH specimens for 3 proteins identified as significant by transcriptomic analysis. Results: A total of 141 human BPH specimens were analyzed for the presence of BCH. Clinical characteristics of non‐BCH and BCH cohorts revealed no significant differences in age, PSA, prostate volume, medical treatment, or comorbidities. Quantitation of cellular subsets by flow cytometry in 11 BCH patients vs. 11 non‐BCH patients demonstrated a significant increase in the ratio of basal to luminal epithelia in patients with BCH (P <0.05), but no significant differences in the total number of leukocytes. RNA‐seq data from flow cytometry isolated basal epithelia from patients with and without BCH were subjected to gene set enrichment analysis of differentially expressed genes, which revealed increased expression of members of the epidermal differentiation complex. Transcriptomic data were complemented by immunohistochemistry for members of the epidermal differentiation complex, revealing a morphological similarity to other stratified squamous epithelial layers. Conclusions: Increased expression of epidermal differentiation complex members and altered epithelial stratification resembles the progression of other metaplastic diseases. These data provide insight into the plasticity of the human prostate epithelium and suggest a classification of basal cell hyperplasia as a metaplasia.
June 2017

Differentiation - Isolation and analysis of discrete human prostate cellular populations

Strand D W, Aaron L, Henry G, Franco O E, Hayward SW
The use of lineage tracing in transgenic mouse models has revealed an abundance of subcellular phenotypes responsible for maintaining prostate homeostasis. The ability to use fresh human tissues to examine the hypotheses generated by these mouse experiments has been greatly enhanced by technical advances in tissue processing, flow cytometry and cell culture. We describe in detail the optimization of protocols for each of these areas to facilitate research on solving human prostate diseases through the analysis of human tissue.
April 2016

JoVE - Endothelial cell tube formation assay for the in vitro study of angiogenesis

DeCicco-Skinner KL, Henry GH, Cataisson C, Tabib T, Gwilliam JC, Watson NJ, Bullwinkle EM, Falkenburg L, O’Neill RC, Morin A, Wiest JS
Angiogenesis is a vital process for normal tissue development and wound healing, but is also associated with a variety of pathological conditions. Using this protocol, angiogenesis may be measured in vitro in a fast, quantifiable manner. Primary or immortalized endothelial cells are mixed with conditioned media and plated on basement membrane matrix. The endothelial cells form capillary like structures in response to angiogenic signals found in conditioned media. The tube formation occurs quickly with endothelial cells beginning to align themselves within 1 hr and lumen-containing tubules beginning to appear within 2 hr. Tubes can be visualized using a phase contrast inverted microscope, or the cells can be treated with calcein AM prior to the assay and tubes visualized through fluorescence or confocal microscopy. The number of branch sites/nodes, loops/meshes, or number or length of tubes formed can be easily quantified as a measure of in vitro angiogenesis. In summary, this assay can be used to identify genes and pathways that are involved in the promotion or inhibition of angiogenesis in a rapid, reproducible, and quantitative manner.
September 2014


    NextGen Omics, Spatial & Data US - March 2026

    From Spatial Transcriptomics to Multimodal Discovery: Scaling AI Driven Genomics on Manifold

    Mohta V, Farhi S, Henry GH
    ORAL PRESENTATION


    EU Biobank Week - April 2024

    Efficiently Analyzing Population-Scale Genomics Data

    Sedlakova, A, Henry GH
    ORAL PRESENTATION


    ACMG - March 2024

    Automated Genome Interpretation Solution to Accelerate Diagnostic Decisions via Intelliseq GeneSpect™ Reporter

    Szklarczyk-Smolana K, Pacewicz K, Henry GH
    ORAL PRESENTATION


    BioTechX Europe - October 2023

    Bridging the Gap: Solutions for Data Integration, Security, and Collaborative Exploration in Precision Medicine

    Rao A, Henry GH
    ORAL PRESENTATION


      Precision Medicine Leaders Summit: Advances in Single Cell & Spatial Biology - September 2023

      Democratizing Access to Single-Cell RNA Sequencing with the Parse Biosciences Evercode Platform

      Henry GH, Roco C
      ORAL PRESENTATION


      Precision Medicine Leaders Summit: Advances in Single Cell & Spatial Biology - September 2023

      Innovation Panel: Building the Spatial Biology Ecosystem

      Enderlein C, Clark JN, Emanuel G, Henry GH, Kim J
      PANELIST


      BioIT World - May 2023

      Towards Precision Medicine: Datasets, Computation, and Data Integration for Patient Subsetting Research - Part I

      Busby BR, Chu E, Floden E, Henry GH, Huitt E
      PANELIST


        BioIT World - May 2023

        Achieving FAIRness with Multimodal Data

        Busby BR, Dawson E, Gillis M, Henry GH, Holt R, Neilley V
        PANELIST


        Cold Spring Harbor: Single Cell Analysis - November 2019

        A Cellular Atlas of Human Prostate Disease

        Henry GH, Malewska A, Malladi VS, Lee J, Gahan JC, Reese J, Strand DW
        POSTER


        American Urological Association: Annual Meeting - May 2019

        Cellular pathogenesis of human BPH

        Henry G, Malewska A, Binoy Joseph D, Roehrborn C, Hutchinson R, Vezina C, Strand D
        POSTER


        Collaborating for the Advancement of Interdisciplinary Research in Benign Urology: Meeting - December 2018

        Building a comprehensive cellular anatomy of the normal and diseased human prostateia

        Henry GH, Malewska A, Joseph DB, Malladi VS, Lee J, Torrealba J, Mauck RJ, Gahan JC, Raj JV, Roehrborn CG, Hon GC, MacConmara MP, Reese JC, Hutchinson RC, Vezina CM, Strand DW
        POSTER


        Society for Basic Urologic Research: Annual Meeting - November 2018

        A Cellular Anatomy of the Normal Human Prostate and BPH

        Henry G, Malewska A, Binoy Joseph D, Malladi V, Lee J, Gahan J, Mauck R, Raj G, Roehrborn C, Hon G, Reese J, Hutchinson R, Vezina C, Strand D
        POSTER


        10x Genomics User Group Meeting: Houston - May 2018

        Determining Cellular Heterogeneity in Human Prostate using the Chromium™ Single Cell 3’ Solution

        Henry GH
        ORAL PRESENTATION


        FlowTex Conference - February 2018

        Determining cellular heterogeneity in human prostate with flow cytometry and single-cell RNA-sequencing

        Henry GH
        ORAL PRESENTATION


        North Texas Flow Cytometry Conference - December 2017

        Determining cellular heterogeneity in human prostate with flow cytometry and single-cell RNA-sequencing

        Henry GH
        ORAL PRESENTATION


        Society for Basic Urologic Research: Annual Meeting - November 2017

        Pathogenesis of Inflammation in Human BPH

        Henry G, Malewska A, Hutchinson R, Gahan J, Mauck R, Torrealba J, Francis F, Roehrborn C, Strand D
        POSTER


          North Texas Flow Cytometry Conference - December 2016

          Deconstructing BPH Phenotypes: Molecular Pathogenesis of Basal Hyperplasia

          Henry GH
          ORAL PRESENTATION


          Society for Basic Urologic Research: Annual Meeting - November 2016

          Deconstructing BPH phenotypes

          Henry G, Malewska A, Mauck R, Torrealba J, Roehrborn C, Strand D
          POSTER


          Society for Basic Urologic Research: Annual Meeting - November 2015

          Cell-specific responses to inflammation in BPH

          Henry G, Malewska A, Mauck R, Roerborn C, Strand D
          POSTER


            American Association of Cancer Research: Annual Meeting - April 2014

            Adipocytes, Obesity and the Multiple Myeloma Microenvironment

            Henry GH, Watson NJ, O’Neill R, Tabib T, Bullwinkle EM, DeCicco-Skinner KL
            POSTER


              Open Source

              A collection of open source visualizations, code, and data that I created or contributed to.

              cellxgene: Single cell analysis of mouse and human prostate reveals novel fibroblasts with specialized distribution and microenvironment interactions

              Single-cell RNA-sequencing of adult human prostates and urethras from organ donors, and BPH (glandular and stromal) patients as well as adult mouse lower urinary tracts.

              Read more..


              RNA-seq Analytic Pipeline for GUDMAP/RBK

              This pipeline conducts end-to-end RNA-seq analysis on replicates stored in the GenitoUrinary Development Molecular Anatomy Project and ReBuilding the Kidney consortium. This pipeline was created in a collaboration between the Strand Lab and Bioinformatics Core Facility (BICF) at UT Southwestern Medical Center.This pipeline conducts end-to-end RNA-seq analysis on replicates stored in the GenitoUrinary Development Molecular Anatomy Project and ReBuilding the Kidney consortium. This pipeline was created in a collaboration between the Strand Lab and Bioinformatics Core Facility (BICF) at UT Southwestern Medical Center.

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              Strand Lab analysis of single-cell RNA sequencing

              This code was used for the single-cell RNA-sequencing analysis in the Strand Lab at UT Southwestern Medical Center

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              BICF Cellranger count Analysis Workflow

              BICF Cellranger count Analysis Workflow is a wrapper for the cellranger count tool from 10x Genomics. This pipeline, used by the Bioinformatics Core Facility at UT Southwestern, takes fastq files from 10x Genomics single-cell gene expression libraries and passes them to cellranger count, managing parallelization of multiple runs, as well as, aggregation as appropriate. This pipeline is primarily used with a SLURM cluster on BioHPC, but it should be able to run on any system that Nextflow supports. Additionally, this pipeline is designed to work using a simple web interface.

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              GEO: Human prostate luminal epithelia adopt a club-like state in response to low androgen levels

              Spatial transcriptomics of treatment naive and 5-alpha reductase inhibitior treated human BPH tissue

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              GEO: Single cell RNA-sequencing of verumontanum region and peripheral zone of normal human prostate

              Dissected verumontanum region and peripheral zone region from a normal human prostate sample were digested into single-cell suspensions, cells were subject to single-cell RNA-sequencing using the 10x Genomics platform

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              GEO: Single-cell RNA-sequencing of adult human normal and BPH (glandular and stroma) prostates and urethra

              Single-cell RNA-sequencing of adult human prostates and urethras from organ donors, and BPH (glandular and stromal) patients.

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              GEO: Single-cell RNA-sequencing of adult mouse lower urinary tracts v2

              Single-cell RNA-sequencing of adult mouse prostates and urethras.

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              GUDMAP: Single cell analysis of mouse and human prostate reveals novel fibroblasts with specialized distribution and microenvironment interactions

              Sequencing data relating to the in preparation publication: 'Single cell analysis of mouse and human prostate reveals novel fibroblasts with specialized distribution and microenvironment interactions'

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              Education

              American University

              Masters of Science
              Biology

              Graduated 2014

              Eckerd College

              Bachelors of Science
              Biomedical Molecular Biology

              Graduated 2009